LGI1 Antikörper (AA 35-557) (Fluoro488)

Produktnummer ABIN8005801

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-LGI1 Antikörper (ABIN8005801) detektiert spezifisch LGI1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Human und Ratte.

Kurzübersicht für LGI1 Antikörper (AA 35-557) (Fluoro488) (ABIN8005801)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LGI1 Antikörper (Fluoro488)

Bindungsspezifität: AA 35-557

Verwendungszweck: Anti-Lgi1/EPT/LGI1 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Lgi1/EPT/LGI1 recombinant protein (Position: K35-A557).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Andere Bezeichnung: LGI1

Hintergrund:

Background: Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

Gene Full Name: leucine rich glioma inactivated 1

Gen-ID: 9211

UniProt: O95970