LRRC1 Antikörper (AA 120-497) (Cy3)

Produktnummer ABIN8005457

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LRRC1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für LRRC1 Antikörper (AA 120-497) (Cy3) (ABIN8005457)

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LRRC1 Antikörper (Cy3)

Bindungsspezifität: AA 120-497

Verwendungszweck: Anti-LRRC1 Antibody Cy3 Conjugated

Homologie: Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC1 recombinant protein (Position: L120-R497). Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LRRC1

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Andere Bezeichnung: LRRC1

Hintergrund:

Background: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.

Gene Full Name: leucine rich repeat containing 1

Gen-ID: 55227

UniProt: Q9BTT6