LEPREL1 Antikörper (AA 106-494) (Biotin)

Produktnummer ABIN8005346

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LEPREL1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für LEPREL1 Antikörper (AA 106-494) (Biotin) (ABIN8005346)

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEPREL1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-LEPREL1 Antikörper (Biotin)

Bindungsspezifität: AA 106-494

Verwendungszweck: Anti-P3H2 Antibody Biotin Conjugated

Homologie: Human P3H2 shares 88.9%,89.5% amino acid (aa) sequence identity with mouse,rat P3H2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human P3H2 recombinant protein (Position: E106-R494). Human P3H2 shares 88.9% and 89.5% amino acid (aa) sequence identity with mouse and rat P3H2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LEPREL1

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Andere Bezeichnung: P3H2

Hintergrund:

Background: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: prolyl 3-hydroxylase 2

Gen-ID: 55214

UniProt: Q8IVL5