LDHD Antikörper (AA 56-498) (PE)

Produktnummer ABIN8004937

Der PE-konjugierte Kaninchen Polyklonal anti-LDHD Antikörper (ABIN8004937) detektiert spezifisch LDHD in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für LDHD Antikörper (AA 56-498) (PE) (ABIN8004937)

Target: LDHD (Lactate Dehydrogenase D (LDHD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDHD Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LDHD Antikörper (PE)

Bindungsspezifität: AA 56-498

Verwendungszweck: Anti-LDHD Antibody PE Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LDHD recombinant protein (Position: R56-Q498).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LDHD

Target: LDHD (Lactate Dehydrogenase D (LDHD))

Andere Bezeichnung: LDHD

Hintergrund:

Background: Two naturally occurring forms of lactate dehydrogenase with similar but unique substrate specificities have been isolated in lower organisms including invertebrates, fungi, and prokaryotes. These dehydrogenase enzymes are L-lactate dehydrogenase and D-lactate dehydrogenase (LDHD) that are specific to the L and D isomers of lactate, respectively (PMID: 12127981). In lactic acid bacteria, LDHD plays a key role in anaerobic energy metabolism (PMID: 497162). Despite the identification of D-lactate and other D-2-hydroxyacids in prokaryotes, and the obvious connections and similarities to vertebrate metabolic pathways, very few mammalian D-2-hydroxyacid dehydrogenases have been found. LDHD has 2 isoforms with the molecular weight of 52 and 54 kDa, and can be detected as 45-54 kDa.

Gene Full Name: lactate dehydrogenase D

Gen-ID: 197257

UniProt: Q86WU2

Pathways: Ribonucleoside Biosynthetic Process