KLF6 Antikörper (AA 38-205) (APC)

Produktnummer ABIN8004771

Der Kaninchen Polyklonal anti-KLF6 Antikörper wird verwendet zum Nachweis von KLF6 in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für KLF6 Antikörper (AA 38-205) (APC) (ABIN8004771)

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF6 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-KLF6 Antikörper (APC)

Bindungsspezifität: AA 38-205

Verwendungszweck: Anti-KLF6 Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human KLF6 shares 92%,90% amino acid (aa) sequences identity with mouse,rat KLF6,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Andere Bezeichnung: KLF6

Hintergrund:

Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

Gene Full Name: KLF transcription factor 6

Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

Gen-ID: 1316

UniProt: Q99612