KLC1 Antikörper (AA 1-537) (HRP)

Produktnummer ABIN8004549

Der Kaninchen Polyklonal anti-KLC1 Antikörper wird verwendet zum Nachweis von KLC1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für KLC1 Antikörper (AA 1-537) (HRP) (ABIN8004549)

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLC1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-KLC1 Antikörper (HRP)

Bindungsspezifität: AA 1-537

Verwendungszweck: Anti-KLC1 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human KLC1 recombinant protein (Position: M1-D537).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KLC1

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Andere Bezeichnung: KLC1

Hintergrund:

Background: Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

Gene Full Name: kinesin light chain 1

Gen-ID: 3831

UniProt: Q07866

Pathways: Ribonucleoprotein Complex Subunit Organization