KIF2C Antikörper (AA 531-725) (Biotin)
Kurzübersicht für KIF2C Antikörper (AA 531-725) (Biotin) (ABIN8004477)
Target
Alle KIF2C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 531-725
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Verwendungszweck
- Anti-MCAK/KIF2C Antibody Biotin Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human MCAK shares 87% amino acid (aa) sequence identity with both mouse,rat MCAK.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MCAK recombinant protein (Position: G531-Q725). Human MCAK shares 87% amino acid (aa) sequence identity with both mouse and rat MCAK.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- KIF2C (Kinesin Family Member 2C (KIF2C))
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Andere Bezeichnung
- KIF2C
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Hintergrund
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Background: Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. KIF2C uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.
Gene Full Name: kinesin family member 2C
Sequence Similarities: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
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Gen-ID
- 11004
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UniProt
- Q99661
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Pathways
- Microtubule Dynamics
Target
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