KIAA1524 Antikörper (C-Term) (HRP)

Produktnummer ABIN8004351

Der Kaninchen Polyklonal anti-KIAA1524 Antikörper wird verwendet zum Nachweis von KIAA1524 in Proben von Human und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für KIAA1524 Antikörper (C-Term) (HRP) (ABIN8004351)

Target: KIAA1524

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIAA1524 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-KIAA1524 Antikörper (HRP)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-p90 Autoantigen/KIAA1524 CIP2A Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by three amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA1524, different from the related mouse sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KIAA1524

Target: KIAA1524

Andere Bezeichnung: CIP2A

Hintergrund:

Background: Protein CIP2A, also known as cancerous inhibitor of PP2A  (CIP2A), is a protein that in humans is encoded by the KIAA1524 gene. CIP2A is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression of CIP2A promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

Gene Full Name: cellular inhibitor of PP2A

Gen-ID: 57650

UniProt: Q8TCG1