Cyclic GMP Antikörper

Produktnummer ABIN750733

Produktdetails anti-Cyclic GMP Antikörper

Target: Cyclic GMP (cGMP)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclic GMP Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.

Kreuzreaktivität: Ratte

Kreuzreaktivität (Details): cGMP

Aufreinigung: Purified by Protein A.

Immunogen: OVA conjugated cGMP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Cyclic GMP

Target: Cyclic GMP (cGMP)

Andere Bezeichnung: Cgmp (cGMP Produkte)

Substanzklasse: Chemical

Hintergrund:

Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.

Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).