KLHL12 Antikörper (AA 27-331) (HRP)

Produktnummer ABIN8004043

Der HRP-konjugierte Maus Monoklonal anti-KLHL12 Antikörper (Klon 2G11D1) (ABIN8004043) detektiert spezifisch KLHL12 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für KLHL12 Antikörper (AA 27-331) (HRP) (ABIN8004043)

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KLHL12 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 2G11D1

Produktdetails anti-KLHL12 Antikörper (HRP)

Bindungsspezifität: AA 27-331

Verwendungszweck: Anti-KLHL12 Antibody (monoclonal, 2G11D1) HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human KLHL12 recombinant protein (Position: R27-I331).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Andere Bezeichnung: KLHL12

Hintergrund:

Background: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.

Gene Full Name: kelch like family member 12

Gen-ID: 59349

UniProt: Q53G59