JUP Antikörper (AA 556-745) (Fluoro550)

Produktnummer ABIN8003721

Der Kaninchen Polyklonal anti-JUP Antikörper wird verwendet zum Nachweis von JUP in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für JUP Antikörper (AA 556-745) (Fluoro550) (ABIN8003721)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JUP Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-JUP Antikörper (Fluoro550)

Bindungsspezifität: AA 556-745

Verwendungszweck: Anti-gamma Catenin/JUP Antibody Fluoro550 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse,rat gamma Catenin.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: JUP

Hintergrund:

Background: Junction plakoglobin (JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to β-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Gene Full Name: junction plakoglobin

Sequence Similarities: Belongs to the beta-catenin family.

Gen-ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location