IDH3G Antikörper (AA 92-420) (PE)

Produktnummer ABIN8003473

Der PE-konjugierte Kaninchen Polyklonal anti-IDH3G Antikörper (ABIN8003473) detektiert spezifisch IDH3G in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für IDH3G Antikörper (AA 92-420) (PE) (ABIN8003473)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH3G Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-IDH3G Antikörper (PE)

Bindungsspezifität: AA 92-420

Verwendungszweck: Anti-IDH3G Antibody PE Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PAIP1 recombinant protein (Position: R92-Q420). Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Andere Bezeichnung: IDH3G

Hintergrund:

Background: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

Gen-ID: 3421

UniProt: P51553