ISOC2 Antikörper (AA 1-205) (PE)

Produktnummer ABIN8003374

Der PE-konjugierte Kaninchen Polyklonal anti-ISOC2 Antikörper (ABIN8003374) detektiert spezifisch ISOC2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ISOC2 Antikörper (AA 1-205) (PE) (ABIN8003374)

Target: ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISOC2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ISOC2 Antikörper (PE)

Bindungsspezifität: AA 1-205

Verwendungszweck: Anti-ISOC2 Antibody PE Conjugated

Homologie: Human ISOC2 shares 84.2%,75% amino acid (aa) sequence identity with mouse,rat ISOC2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ISOC2

Target: ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Andere Bezeichnung: ISOC2

Hintergrund:

Background: ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.

Gene Full Name: isochorismatase domain containing 2

Gen-ID: 79763

UniProt: Q96AB3