ICA1 Antikörper (Middle Region) (Fluoro647)

Produktnummer ABIN8003353

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-ICA1 Antikörper (ABIN8003353) detektiert spezifisch ICA1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ICA1 Antikörper (Middle Region) (Fluoro647) (ABIN8003353)

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICA1 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ICA1 Antikörper (Fluoro647)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-ICA1 Antibody Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ICA1, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ICA1

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Andere Bezeichnung: ICA1

Hintergrund:

Background: Islet cell autoantigen 1 is a protein that in humans is encoded by the ICA1 gene. It is mapped to 7p22. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. What's more, this protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene.

Gene Full Name: islet cell autoantigen 1

Sequence Similarities: Belongs to the CTCF zinc-finger protein family.

Gen-ID: 3382

UniProt: Q05084