ITGA4 Antikörper (AA 41-963)

Produktnummer ABIN8000340

Der Kaninchen Polyklonal anti-ITGA4 Antikörper wird verwendet zum Nachweis von ITGA4 in Proben von Maus und Ratte. Er wurde validiert für FACS, WB und ELISA.

Kurzübersicht für ITGA4 Antikörper (AA 41-963) (ABIN8000340)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails anti-ITGA4 Antikörper

Bindungsspezifität: AA 41-963

Verwendungszweck: Anti-Integrin Alpha 4/Itga4 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.

Produktmerkmale: Anti-Integrin Alpha 4/Itga4 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Integrin Alpha 4/Itga4 recombinant protein (Position: Y41-D963). Mouse Itga4 shares 85.2% amino acid (aa) sequence identity with human Itga4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: Itga4

Hintergrund:

Background: CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: integrin alpha 4

Molekulargewicht: 150-180 kDa

Gen-ID: 16401

UniProt: Q00651

Pathways: Integrin Complex