IGF2R Antikörper (AA 424-529) (HRP)

Produktnummer ABIN8000061

Der Maus Monoklonal anti-IGF2R Antikörper wird verwendet zum Nachweis von IGF2R in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für IGF2R Antikörper (AA 424-529) (HRP) (ABIN8000061)

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF2R Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 4I11

Produktdetails anti-IGF2R Antikörper (HRP)

Bindungsspezifität: AA 424-529

Verwendungszweck: Anti-IGF2R Antibody (monoclonal, 4I11) HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human IGF2R recombinant protein (Position: F424-R529).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Andere Bezeichnung: IGF2R

Hintergrund:

Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Gene Full Name: insulin like growth factor 2 receptor

Gen-ID: 3482

UniProt: P11717