HSD17B10 Antikörper (AA 48-261) (HRP)

Produktnummer ABIN7998769

Der Kaninchen Polyklonal anti-HSD17B10 Antikörper wird verwendet zum Nachweis von HSD17B10 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für HSD17B10 Antikörper (AA 48-261) (HRP) (ABIN7998769)

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B10 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-HSD17B10 Antikörper (HRP)

Bindungsspezifität: AA 48-261

Verwendungszweck: Anti-ERAB/HSD17B10 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human ERAB shares 87%,88% amino acid (aa) sequence identity with mouse,rat ERAB,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ERAB recombinant protein (Position: E48-P261). Human ERAB shares 87% and 88% amino acid (aa) sequence identity with mouse and rat ERAB, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Andere Bezeichnung: HSD17B10

Hintergrund:

Background: ERAB is also known as HSD17B10 or HADH2. This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Gene Full Name: hydroxysteroid 17-beta dehydrogenase 10

Gen-ID: 3028

UniProt: Q99714