HSD11B1 Antikörper (AA 30-292) (APC)
Kurzübersicht für HSD11B1 Antikörper (AA 30-292) (APC) (ABIN7998704)
Target
Alle HSD11B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-292
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Verwendungszweck
- Anti-HSD11B1 Antibody APC Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human HSD11B1 recombinant protein (Position: E30-K292).
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Isotyp
- IgG
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anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibody
HSD11B1 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 201-292) antibodyHSD11B1 Reaktivität: Human, Ratte, Maus, Pferd ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (Internal Region) antibodyHSD11B1 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2C10 unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (C-Term) antibodyHSD11B1 Reaktivität: Human WB, ICC, IF, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Schaf, Rind (Kuh), Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) antibodyHSD11B1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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Andere Bezeichnung
- HSD11B1
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Hintergrund
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Background: 11beta-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. It is inhibited by carbenoxolone, a drug typically used in the treatment of peptic ulcers. Tannin et al.(1991) localized the HSD11B1 gene to chromosome 1. The localization was confirmed by isolating the gene from a chromosome 1-specific library using the cDNA as a probe. Schutte et al.(2000) mapped the HSD11B1 gene to 1q32-q41.
Gene Full Name: hydroxysteroid 11-beta dehydrogenase 1
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Gen-ID
- 3290
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UniProt
- P28845
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
Target
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