HYAL3 Antikörper (C-Term) (Cy3)

Produktnummer ABIN7998555

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HYAL3 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für HYAL3 Antikörper (C-Term) (Cy3) (ABIN7998555)

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL3 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HYAL3 Antikörper (Cy3)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Hyaluronidase-3 HYAL3 Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by three amino acids,and different from the related mouse sequence by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3, different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Andere Bezeichnung: HYAL3

Hintergrund:

Background: HYAL3 (hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

Gene Full Name: hyaluronidase 3

Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

Gen-ID: 8372

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process