HTRA2 Antikörper (AA 30-458) (APC)

Produktnummer ABIN7998396

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HTRA2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HTRA2 Antikörper (AA 30-458) (APC) (ABIN7998396)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HTRA2 Antikörper (APC)

Bindungsspezifität: AA 30-458

Verwendungszweck: Anti-HTRA2 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HTRA2 recombinant protein (Position: R30-E458). Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HTRA2

Hintergrund:

Background: Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: HtrA serine peptidase 2

Gen-ID: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity