HNF1B Antikörper (C-Term) (APC)

Produktnummer ABIN7998000

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HNF1B in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für HNF1B Antikörper (C-Term) (APC) (ABIN7998000)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1B Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HNF1B Antikörper (APC)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-HNF1 beta/HNF1B Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HNF1 beta, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Andere Bezeichnung: HNF1B

Hintergrund:

Background: HNF1 homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. It is a member of the homeodomain-containing superfamily of transcription factors. This gene is mapped to 17q12. The HNF1B protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1. HNF1B functions as both a classic transcriptional activator and as a bookmarking factor that marks target genes for rapid transcriptional reactivation after mitosis. HNF1B also can regulate renal tubulogenesis by controlling expression of SOC3. Mutation of HNF1B that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).

Gene Full Name: HNF1 homeobox B

Sequence Similarities: Belongs to the HNF1 homeobox family.

Gen-ID: 6928

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation