BCR Antikörper (AA 1201-1271) (Cy5)
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- Target Alle BCR Antikörper anzeigen
- BCR (Breakpoint Cluster Region (BCR))
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Bindungsspezifität
- AA 1201-1271
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BCR Antikörper ist konjugiert mit Cy5
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Bcr
- Isotyp
- IgG
- Top Product
- Discover our top product BCR Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- BCR (Breakpoint Cluster Region (BCR))
- Andere Bezeichnung
- Bcr (BCR Produkte)
- Synonyme
- si:dkey-83d9.7 antikoerper, zK83D9.7 antikoerper, BCR antikoerper, ALL antikoerper, BCR1 antikoerper, CML antikoerper, D22S11 antikoerper, D22S662 antikoerper, PHL antikoerper, 5133400C09Rik antikoerper, AI561783 antikoerper, AI853148 antikoerper, mKIAA3017 antikoerper, breakpoint cluster region antikoerper, BCR, RhoGEF and GTPase activating protein antikoerper, bcr antikoerper, BCR antikoerper, Bcr antikoerper
- Hintergrund
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Synonyms: ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.
Background: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
- Gen-ID
- 613
- Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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