HSPB2 Antikörper (AA 1-182) (Fluoro647)

Produktnummer ABIN7996240

Der Kaninchen Polyklonal anti-HSPB2 Antikörper wird verwendet zum Nachweis von HSPB2 in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für HSPB2 Antikörper (AA 1-182) (Fluoro647) (ABIN7996240)

Target: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB2 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HSPB2 Antikörper (Fluoro647)

Bindungsspezifität: AA 1-182

Verwendungszweck: Anti-HSPB2 Antibody Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human HSPB2 shares 97.3% amino acid (aa) sequence identity with both mouse,rat HSPB2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HSPB2 recombinant protein (Position: M1-P182). Human HSPB2 shares 97.3% amino acid (aa) sequence identity with both mouse and rat HSPB2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HSPB2

Target: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Andere Bezeichnung: HSPB2

Hintergrund:

Background: Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al. (1997) identified a gene transcribed in the opposite ion. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al. (1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2 is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

Gene Full Name: heat shock protein family B (small) member 2

Sequence Similarities: Belongs to the small heat shock protein (HSP20) family.

Gen-ID: 3316

UniProt: Q16082