H2AFY Antikörper (AA 180-301) (Biotin)

Produktnummer ABIN7995933

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch H2AFY in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für H2AFY Antikörper (AA 180-301) (Biotin) (ABIN7995933)

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFY Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-H2AFY Antikörper (Biotin)

Bindungsspezifität: AA 180-301

Verwendungszweck: Anti-H2AFY/MACROH2A1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse,rat MACROH2A1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human H2AFY/MACROH2A1 recombinant protein (Position: A180-K301). Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse and rat MACROH2A1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu H2AFY

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Andere Bezeichnung: MACROH2A1

Hintergrund:

Background: Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: macroH2A.1 histone

Gen-ID: 9555

UniProt: O75367