Golgin B1 (GOLGB1) (AA 153-950) Antikörper (HRP)

Produktnummer ABIN7994982

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Golgin B1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Golgin B1 (GOLGB1) (AA 153-950) Antikörper (HRP) (ABIN7994982)

Target: Golgin B1 (GOLGB1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 153-950

Verwendungszweck: Anti-Giantin/GOLGB1 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Giantin/GOLGB1 recombinant protein (Position: L153-E950).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Golgin B1 (GOLGB1)

Andere Bezeichnung: GOLGB1

Hintergrund:

Background: Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. GOLGB1, also known as Giantin and Macrogolgin, is a 360 to 400 kDa member of the Golgin protein family. GOLGB1 is an integral component of the Golgi membrane that associates with the cytoskeleton. It may be involved in both forming intercisternal cross-bridges that mediate stacking in Golgi complexes, and in reorganizing the complexes after they fragment during mitosis. GOLGB1 has also been identified as an autoantigen in chronic rheumatoid arthritis, and in the autoimmune disease Sjoegren syndrome. Human GOLGB1 is 3259 amino acids (aa) in length, and over aa 1596-1702, shares 92 % and 91 % sequence identity with its mouse and rat orthologs, respectively.

Gene Full Name: golgin B1

Gen-ID: 2804

UniProt: Q14789

Pathways: SARS-CoV-2 Protein Interaktom