GLDC Antikörper (AA 574-1020) (FITC)

Produktnummer ABIN7994552

Der FITC-konjugierte Maus Monoklonal anti-GLDC Antikörper (Klon 3D3D3) (ABIN7994552) detektiert spezifisch GLDC in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GLDC Antikörper (AA 574-1020) (FITC) (ABIN7994552)

Target: GLDC (Glycine Dehydrogenase (GLDC))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLDC Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: 3D3D3

Produktdetails anti-GLDC Antikörper (FITC)

Bindungsspezifität: AA 574-1020

Verwendungszweck: Anti-Glycine decarboxylase/GLDC Antibody (monoclonal, 3D3D3) FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Glycine decarboxylase/GLDC recombinant protein (Position: K574-S1020).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GLDC

Target: GLDC (Glycine Dehydrogenase (GLDC))

Andere Bezeichnung: GLDC

Hintergrund:

Background: Glycine decarboxylase also known as glycine cleavage system P protein or glycine dehydrogenase is an enzyme that in humans is encoded by the GLDC gene. Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Gene Full Name: glycine decarboxylase

Gen-ID: 2731

UniProt: P23378