Glutaredoxin 2 Antikörper (Middle Region) (HRP)

Produktnummer ABIN7994113

Der Kaninchen Polyklonal anti-Glutaredoxin 2 Antikörper wird verwendet zum Nachweis von Glutaredoxin 2 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Glutaredoxin 2 Antikörper (Middle Region) (HRP) (ABIN7994113)

Target: Glutaredoxin 2 (GRX2)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Glutaredoxin 2 Antikörper (HRP)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-Glutaredoxin 2/GLRX2 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by two amino acids,and from the related mouse sequence by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Glutaredoxin 2, different from the related rat sequence by two amino acids, and from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Glutaredoxin 2

Target: Glutaredoxin 2 (GRX2)

Andere Bezeichnung: GLRX2

Hintergrund:

Background: GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins (e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al. (2001) and Gladyshev et al. (2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al. (2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon (exon 1B) located upstream from the first exon used by the GLRX2A transcript (exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al. (2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

Gene Full Name: glutaredoxin 2

Sequence Similarities: Belongs to the glutaredoxin family.

Gen-ID: 51022

UniProt: Q9NS18

Pathways: Cell RedoxHomeostasis