GPT2 Antikörper (AA 56-523) (Fluoro488)

Produktnummer ABIN7993954

Der Kaninchen Polyklonal anti-GPT2 Antikörper wird verwendet zum Nachweis von GPT2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für GPT2 Antikörper (AA 56-523) (Fluoro488) (ABIN7993954)

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPT2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GPT2 Antikörper (Fluoro488)

Bindungsspezifität: AA 56-523

Verwendungszweck: Anti-GPT2 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human GPT2 shares 94.4% amino acid (aa) sequence identity with mouse GPT2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GPT2 recombinant protein (Position: Q56-A523). Human GPT2 shares 94.4% amino acid (aa) sequence identity with mouse GPT2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GPT2

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Andere Bezeichnung: GPT2

Hintergrund:

Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

Gene Full Name: glutamic--pyruvic transaminase 2

Gen-ID: 84706

UniProt: Q8TD30