Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515) (APC)

Produktnummer ABIN7993462

Der Kaninchen Polyklonal anti-Glucose-6-Phosphate Dehydrogenase Antikörper wird verwendet zum Nachweis von Glucose-6-Phosphate Dehydrogenase in Proben von Human und Maus. Er wurde validiert für FACS.

Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (AA 315-515) (APC) (ABIN7993462)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper (APC)

Bindungsspezifität: AA 315-515

Verwendungszweck: Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human G6PD shares 95%,96% amino acid (aa) sequences identity with mouse,rat G6PD,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD

Hintergrund:

Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

Gene Full Name: glucose-6-phosphate dehydrogenase

Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

Gen-ID: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones