GCKR Antikörper (AA 8-569) (Fluoro550)

Produktnummer ABIN7993414

Der Kaninchen Polyklonal anti-GCKR Antikörper wird verwendet zum Nachweis von GCKR in Proben von Human, Ratte und Maus. Er wurde validiert für FACS.

Kurzübersicht für GCKR Antikörper (AA 8-569) (Fluoro550) (ABIN7993414)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCKR Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GCKR Antikörper (Fluoro550)

Bindungsspezifität: AA 8-569

Verwendungszweck: Anti-GCKR Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GCKR recombinant protein (Position: Q8-Q569).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Andere Bezeichnung: GCKR

Hintergrund:

Background: The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Gene Full Name: glucokinase regulator

Gen-ID: 2646

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus