GFRA2 Antikörper (AA 30-425) (Fluoro647)

Produktnummer ABIN7993035

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GFRA2 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für GFRA2 Antikörper (AA 30-425) (Fluoro647) (ABIN7993035)

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA2 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GFRA2 Antikörper (Fluoro647)

Bindungsspezifität: AA 30-425

Verwendungszweck: Anti-GFRA2 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Andere Bezeichnung: GFRA2

Hintergrund:

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: GDNF family receptor alpha 2

Gen-ID: 2675

UniProt: O00451