GATA5 Antikörper (AA 1-397) (APC)

Produktnummer ABIN7992978

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GATA5 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GATA5 Antikörper (AA 1-397) (APC) (ABIN7992978)

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA5 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GATA5 Antikörper (APC)

Bindungsspezifität: AA 1-397

Verwendungszweck: Anti-GATA5 Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GATA5

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Andere Bezeichnung: GATA5

Hintergrund:

Background: Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.

Gene Full Name: GATA binding protein 5

Sequence Similarities: Contains 2 GATA-type zinc fingers.

Gen-ID: 140628

UniProt: Q9BWX5