FYCO1 Antikörper (AA 1-1019) (APC)
Kurzübersicht für FYCO1 Antikörper (AA 1-1019) (APC) (ABIN7992062)
Target
Alle FYCO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-1019
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Verwendungszweck
- Anti-FYCO1 Antibody APC Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human FYCO1 recombinant protein (Position: M1-K1019). Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))
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Andere Bezeichnung
- FYCO1
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Hintergrund
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Background: The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2).
Gene Full Name: FYVE and coiled-coil domain autophagy adaptor 1
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Gen-ID
- 79443
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UniProt
- Q9BQS8
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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