Frataxin Antikörper (AA 20-210) (Biotin)

Produktnummer ABIN7991777

Der Biotin-konjugierte Kaninchen Polyklonal anti-Frataxin Antikörper (ABIN7991777) detektiert spezifisch Frataxin in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Frataxin Antikörper (AA 20-210) (Biotin) (ABIN7991777)

Target: Frataxin (FXN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frataxin Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Frataxin Antikörper (Biotin)

Bindungsspezifität: AA 20-210

Verwendungszweck: Anti-FXN Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human FXN shares 79%,71.4% amino acid (aa) sequence identity with mouse,rat FXN,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FXN recombinant protein (Position: Q20-A210). Human FXN shares 79% and 71.4% amino acid (aa) sequence identity with mouse and rat FXN, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: FXN

Hintergrund:

Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Gene Full Name: frataxin

Gen-ID: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size