Foxk1 Antikörper (AA 175-671) (PE)

Produktnummer ABIN7991455

Der Kaninchen Polyklonal anti-Foxk1 Antikörper wird verwendet zum Nachweis von Foxk1 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für Foxk1 Antikörper (AA 175-671) (PE) (ABIN7991455)

Target: Foxk1 (Forkhead Box K1 (Foxk1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Foxk1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Foxk1 Antikörper (PE)

Bindungsspezifität: AA 175-671

Verwendungszweck: Anti-FOXK1/MNF Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FOXK1/MNF recombinant protein (Position: Q175-E671).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Foxk1

Target: Foxk1 (Forkhead Box K1 (Foxk1))

Andere Bezeichnung: FOXK1

Hintergrund:

Background: Forkhead box protein K1 is a transcription factor of the forkhead box family that in humans is encoded by the FOXK1 gene. It is mapped to 7p22.1. FOXK1 is one of the transcription factors managing the passage from the normal cellular respiration (complete glucose oxidation) to generating ATP and intermediaries for many other biochemical pathways. FOXK1 and its closely relate sibling FOXK2 induce aerobic glycolysis by upregulating the enzymatic machinery required for this (for example, hexokinase-2, phosphofructokinase, pyruvate kinase, and lactate dehydrogenase), while at the same time suppressing further oxidation of pyruvate in the mitochondria by increasing the activity of pyruvate dehydrogenase kinases 1 and 4.

Gene Full Name: forkhead box K1

Gen-ID: 221937

UniProt: P85037