Fission 1 Antikörper (AA 18-152)
Kurzübersicht für Fission 1 Antikörper (AA 18-152) (ABIN7990940)
Target
Alle Fission 1 (FIS1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 18-152
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Verwendungszweck
- Anti-TTC11/FIS1 Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-TTC11/FIS1 Antibody. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human TTC11/FIS1 recombinant protein (Position: E18-S152).
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- Fission 1 (FIS1)
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Andere Bezeichnung
- FIS1
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Hintergrund
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Background: Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. It is mapped to 7q22.1. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphology, the cell cycle, and apoptosis. By extension, the protein is involved in associated diseases, including neurodegenerative diseases and cancers.
Gene Full Name: fission, mitochondrial 1
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Molekulargewicht
- 17 kDa
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Gen-ID
- 51024
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UniProt
- Q9Y3D6
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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