Fatty Acid Synthase Antikörper (AA 1-226) (PE)

Produktnummer ABIN7990033

Der Kaninchen Polyklonal anti-Fatty Acid Synthase Antikörper wird verwendet zum Nachweis von Fatty Acid Synthase in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für Fatty Acid Synthase Antikörper (AA 1-226) (PE) (ABIN7990033)

Target: Fatty Acid Synthase (FASN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Fatty Acid Synthase Antikörper (PE)

Bindungsspezifität: AA 1-226

Verwendungszweck: Anti-Fatty Acid Synthase/FASN Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3%,90.7% amino acid (aa) sequence identity with mouse,rat FASN,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN

Hintergrund:

Background: Fatty acid synthase  (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Gene Full Name: fatty acid synthase

Gen-ID: 2194

UniProt: P49327

Pathways: AMPK Signaling