FOXRED2 Antikörper (AA 44-623) (PE)

Produktnummer ABIN7989538

Der Kaninchen Polyklonal anti-FOXRED2 Antikörper wird verwendet zum Nachweis von FOXRED2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für FOXRED2 Antikörper (AA 44-623) (PE) (ABIN7989538)

Target: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXRED2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-FOXRED2 Antikörper (PE)

Bindungsspezifität: AA 44-623

Verwendungszweck: Anti-FOXRED2 Antibody PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu FOXRED2

Target: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Andere Bezeichnung: FOXRED2

Hintergrund:

Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

Gene Full Name: FAD dependent oxidoreductase domain containing 2

Gen-ID: 80020

UniProt: Q8IWF2

Pathways: SARS-CoV-2 Protein Interaktom