FBXW8 Antikörper (AA 1-598) (HRP)

Produktnummer ABIN7989459

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FBXW8 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für FBXW8 Antikörper (AA 1-598) (HRP) (ABIN7989459)

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW8 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FBXW8 Antikörper (HRP)

Bindungsspezifität: AA 1-598

Verwendungszweck: Anti-FBXW8 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human FBXW8 shares 78.5%,77.4% amino acid (aa) sequence identity with mouse,rat FBXW8,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FBXW8 recombinant protein (Position: M1-V598). Human FBXW8 shares 78.5% and 77.4% amino acid (aa) sequence identity with mouse and rat FBXW8, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FBXW8

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Andere Bezeichnung: FBXW8

Hintergrund:

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: F-box and WD repeat domain containing 8

Gen-ID: 26259

UniProt: Q8N3Y1