EDC4 Antikörper (AA 1082-1388) (APC)

Produktnummer ABIN7987782

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EDC4 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für EDC4 Antikörper (AA 1082-1388) (APC) (ABIN7987782)

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDC4 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-EDC4 Antikörper (APC)

Bindungsspezifität: AA 1082-1388

Verwendungszweck: Anti-EDC4 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human EDC4 recombinant protein (Position: K1082-L1388).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Andere Bezeichnung: EDC4

Hintergrund:

Background: Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjgren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.

Gene Full Name: enhancer of mRNA decapping 4

Gen-ID: 23644

UniProt: Q6P2E9