ECE1 Antikörper (AA 18-233) (APC)

Produktnummer ABIN7987771

Der Kaninchen Polyklonal anti-ECE1 Antikörper wird verwendet zum Nachweis von ECE1 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für ECE1 Antikörper (AA 18-233) (APC) (ABIN7987771)

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECE1 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ECE1 Antikörper (APC)

Bindungsspezifität: AA 18-233

Verwendungszweck: Anti-ECE1 Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human ECE1 shares 94%,93.5% amino acid (aa) sequence identity with mouse,rat ECE1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ECE1 recombinant protein (Position: M18-T233). Human ECE1 shares 94% and 93.5% amino acid (aa) sequence identity with mouse and rat ECE1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ECE1

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Andere Bezeichnung: ECE1

Hintergrund:

Background: Endothelin converting enzyme 1, also known as ECE1, is an enzyme which in humans is encoded by the ECE1 gene. The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Full Name: endothelin converting enzyme 1

Gen-ID: 1889

UniProt: P42892

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling