ELP3/KAT9 Antikörper (C-Term) (APC)

Produktnummer ABIN7987406

Der APC-konjugierte Maus Monoklonal anti-ELP3/KAT9 Antikörper (Klon 8B4) (ABIN7987406) detektiert spezifisch ELP3/KAT9 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ELP3/KAT9 Antikörper (C-Term) (APC) (ABIN7987406)

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ELP3/KAT9 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: 8B4

Produktdetails anti-ELP3/KAT9 Antikörper (APC)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-KAT9/ELP3 Antibody (monoclonal, 8B4) APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequence.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human KAT9/ELP3, identical to the related mouse sequence.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ELP3/KAT9

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Andere Bezeichnung: ELP3

Hintergrund:

Background: Elongator complex protein 3, also named KAT9, is aproteinthat in humans is encoded by theELP3gene. It is mapped to 8p21.1. ELP3 is the catalytichistone acetyltransferasesubunit of theRNA polymeraseII elongator complex, which is a component of the RNA polymerase II (Pol II)holoenzymeand is involved in transcriptional elongation. ELP3 supports the migration and branching ofprojection neuronsthroughacetylationof alpha-tubulin in the developingcerebral cortex. In mammals, ELP3 is important for paternalDNA demethylationafterfertilization.ELP3 is potentially involved in cellular redoxhomeostasisby mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role inchromatin remodelingand is involved in acetylation ofhistones H3and probablyH4.

Gene Full Name: elongator acetyltransferase complex subunit 3

Gen-ID: 55140

UniProt: Q9H9T3