Dynamin 1-Like Antikörper (AA 452-736)

Produktnummer ABIN7986577

Der Kaninchen Polyklonal anti-Dynamin 1-Like Antikörper wird verwendet zum Nachweis von Dynamin 1-Like in Proben von Human und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für Dynamin 1-Like Antikörper (AA 452-736) (ABIN7986577)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: AA 452-736

Verwendungszweck: Anti-DRP1/DNM1L Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-DRP1/DNM1L Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DRP1/DNM1L recombinant protein (Position: Q452-W736).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L

Hintergrund:

Background: Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: dynamin 1 like

Molekulargewicht: 75 kDa

Gen-ID: 10059

UniProt: O00429