DUSP2 Antikörper (AA 1-250) (Fluoro488)

Produktnummer ABIN7986457

Der Kaninchen Polyklonal anti-DUSP2 Antikörper wird verwendet zum Nachweis von DUSP2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für DUSP2 Antikörper (AA 1-250) (Fluoro488) (ABIN7986457)

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-DUSP2 Antikörper (Fluoro488)

Bindungsspezifität: AA 1-250

Verwendungszweck: Anti-DUSP2 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DUSP2 recombinant protein (Position: M1-G250). Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Andere Bezeichnung: DUSP2

Hintergrund:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Gene Full Name: dual specificity phosphatase 2

Gen-ID: 1844

UniProt: Q05923