DRD5 Antikörper (C-Term) (Fluoro647)

Produktnummer ABIN7986282

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DRD5 in FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für DRD5 Antikörper (C-Term) (Fluoro647) (ABIN7986282)

Target: DRD5 (Dopamine Receptor D5 (DRD5))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD5 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-DRD5 Antikörper (Fluoro647)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Dopamine Receptor D5/DRD5 Antibody Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by two amino acids,and from the related human sequence by three amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Dopamine Receptor D5, different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu DRD5

Target: DRD5 (Dopamine Receptor D5 (DRD5))

Andere Bezeichnung: DRD5

Hintergrund:

Background: D (1B) dopamine receptor (DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

Gene Full Name: dopamine receptor D5

Sequence Similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.

Gen-ID: 13492

UniProt: Q8BLD9

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity