DRD4 Antikörper (AA 57-387) (Fluoro488)

Produktnummer ABIN7986253

Der Kaninchen Polyklonal anti-DRD4 Antikörper wird verwendet zum Nachweis von DRD4 in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für DRD4 Antikörper (AA 57-387) (Fluoro488) (ABIN7986253)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD4 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-DRD4 Antikörper (Fluoro488)

Bindungsspezifität: AA 57-387

Verwendungszweck: Anti-DRD4 Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse DRD4 recombinant protein (Position: A57-C387).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Andere Bezeichnung: Drd4

Hintergrund:

Background: D (4) dopamine receptor is a protein that in humans is encoded by the Drd4 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: dopamine receptor D4

Gen-ID: 13491

UniProt: P51436

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity