DISC1 Antikörper (N-Term) (Fluoro594)

Produktnummer ABIN7985745

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DISC1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DISC1 Antikörper (N-Term) (Fluoro594) (ABIN7985745)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DISC1 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-DISC1 Antikörper (Fluoro594)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-DISC1 Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DISC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Andere Bezeichnung: DISC1

Hintergrund:

Background: DISC1 (Disrupted in Schizophrenia 1), is a protein that is encoded by the DISC1 gene in humans. Ma et al. (2002) determined that the mouse Disc1 gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42. Ozeki et al. (2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation, with the highest levels in late embryonic life during development of the cerebral cortex. Millar et al. (2005) showed that DISC1 interacts with the UCR2 domain of phosphodiesterase-4B, implicated in susceptibility to schizophrenia, and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity.

Gene Full Name: DISC1 scaffold protein

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

Gen-ID: 27185

UniProt: Q9NRI5

Pathways: Regulation of Cell Size