Desmocollin 3 Antikörper (AA 87-676) (Biotin)

Produktnummer ABIN7984966

Der Kaninchen Polyklonal anti-Desmocollin 3 Antikörper wird verwendet zum Nachweis von Desmocollin 3 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Desmocollin 3 Antikörper (AA 87-676) (Biotin) (ABIN7984966)

Target: Desmocollin 3 (DSC3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Desmocollin 3 Antikörper (Biotin)

Bindungsspezifität: AA 87-676

Verwendungszweck: Anti-DSC3 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DSC3 recombinant protein (Position: L87-Q676).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Desmocollin 3

Target: Desmocollin 3 (DSC3)

Andere Bezeichnung: DSC3

Hintergrund:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: desmocollin 3

Gen-ID: 1825

UniProt: Q14574