Desmocollin 3 Antikörper (AA 87-676)

Produktnummer ABIN7984965

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Desmocollin 3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Desmocollin 3 Antikörper (AA 87-676) (ABIN7984965)

Target: Desmocollin 3 (DSC3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmocollin 3 Antikörper

Bindungsspezifität: AA 87-676

Verwendungszweck: Anti-DSC3 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-DSC3 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DSC3 recombinant protein (Position: L87-Q676).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Desmocollin 3

Target: Desmocollin 3 (DSC3)

Andere Bezeichnung: DSC3

Hintergrund:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: desmocollin 3

Molekulargewicht: 90-110 kDa

Gen-ID: 1825

UniProt: Q14574