Desmin Antikörper (AA 1-304) (HRP)

Produktnummer ABIN7984937

Der HRP-konjugierte Kaninchen Polyklonal anti-Desmin Antikörper (ABIN7984937) detektiert spezifisch Desmin in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Desmin Antikörper (AA 1-304) (HRP) (ABIN7984937)

Target: Desmin (DES)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmin Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Desmin Antikörper (HRP)

Bindungsspezifität: AA 1-304

Verwendungszweck: Anti-Desmin Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Desmin shares 97% amino acid (aa) sequence identity with both mouse,rat Desmin.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Desmin recombinant protein (Position: M1-T304). Human Desmin shares 97% amino acid (aa) sequence identity with both mouse and rat Desmin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: DES

Hintergrund:

Background: DES, also called desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is the muscle-specific member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is expressed in satellite stem cells and replicating myoblasts. DES is very important in muscle cell architecture and structure since it connects many components of the cytoplasm. It may be also play an important role in mitochondria function. What's more, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions.

Gene Full Name: desmin

Sequence Similarities: Belongs to the intermediate filament family.

Gen-ID: 1674

UniProt: P17661